Circulatory changes in the 13-lined ground squirrel during the hibernating cycle.
نویسندگان
چکیده
0 This paper is a description of the changes which take place in the blood pressure, body temperature, and EKG during the hibernating cycle of the 13-lined ground squirrel (Citellus tridecemlineatus), and the effect of drugs during various parts of this cycle.
منابع مشابه
Transcriptional Activation of p53 during Cold Induced Torpor in the 13-Lined Ground Squirrel Ictidomys tridecemlineatus
The transcription factor p53 is located at the centre of multiple pathways relating the cellular response to stress. Commonly known as a tumor suppressor, it is responsible for initiating diverse actions to protect the integrity of the genome, ranging from cell cycle arrest to apoptosis. This study investigated the regulation of p53 protein in hibernating 13-lined ground squirrel Ictidomys trid...
متن کاملExpression Patterns of Codon Usage and Homopolymers in the 13-Lined Ground Squirrel
Introduction Why Squirrels? The 13-lined ground squirrel, scientifically labeled Ictidomys tridecemlineatus, is a furry squirrel abundant in Minnesota and much of the Midwest. Named for the alternating stripes down its back, the 13-lined squirrel is the namesake of the University of Minnesota Golden Gophers [1]. It lives in tunnels underground rather than in trees like its cousins the tree squi...
متن کاملExpression of a chimeric retroviral-lipase mRNA confers enhanced lipolysis in a hibernating mammal.
Hibernating mammals can survive several months without feeding by limiting their carbohydrate catabolism and using triacylglycerols stored in white adipose tissue (WAT) as their primary source of fuel. Here we show that a lipolytic enzyme normally found in the gut, pancreatic triacylglycerol lipase (PTL), is expressed in WAT of hibernating 13-lined ground squirrels (Spermophilus tridecemlineatu...
متن کاملGenes controlling the metabolic switch in hibernating mammals.
Hibernating mammals have the ability to decrease their metabolic rate and survive up to 6 months without food in an inactive state where body temperatures approach 0 degrees C. In hibernating 13-lined ground squirrels (Spermophilus tridecemlineatus), oxygen consumption holds at 1/30 to 1/50 of the aroused condition and heart rates are as low as 3-10 beats/min, compared with 200-300 beats/min wh...
متن کاملOpposing Activity Changes in AMP Deaminase and AMP-Activated Protein Kinase in the Hibernating Ground Squirrel
Hibernating animals develop fatty liver when active in summertime and undergo a switch to a fat oxidation state in the winter. We hypothesized that this switch might be determined by AMP and the dominance of opposing effects: metabolism through AMP deaminase (AMPD2) (summer) and activation of AMP-activated protein kinase (AMPK) (winter). Liver samples were obtained from 13-lined ground squirrel...
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ورودعنوان ژورنال:
- Technical report.; TR. Arctic Aeromedical Laboratory
دوره 60 24 شماره
صفحات -
تاریخ انتشار 1961